Monday, 10 June 2024

UK: What diabetes health checks should I be getting?

From diabetes.org.uk

Diabetes can cause other health problems that can become serious if not picked up and monitored or treated in the early stages. So regular diabetes health checks – sometimes called your yearly or annual review  –  are part of your routine NHS treatment.

As part of your annual review, these are the health checks you should be offered:

A blood test where enough blood is taken to be sent to the lab to check your:

You should be asked to provide a urine sample that is sent to the lab to check: 

At the appointment you should also have:

  • A foot check which may be done safely once every two years if your last check showed no problems
  • Your weight and height measured to work out your Body Mass Index (BMI)
  • Your blood pressure measured.

Your healthcare team will also ask if you smoke, so you can be offered help to stop.

It may not be at your annual review appointment, and is likely to be done by a different team, but you should also be invited to:

  • A diabetic eye check this is not the same as a sight test at the optician. Photos are taken of your eyes to see how diabetes is affecting them, as it can damage the blood vessels and cause an eye problem called diabetic retinopathy. 

    If your last diabetic eye check was clear, it may be safely offered once every two years rather than once a year. 

If you’ve been finding it hard to manage your blood sugar levels, be kind to yourself. Rather than being tempted to skip your health checks, see appointments as an opportunity to be as honest as you can with your healthcare team – and ask for help.  

Early treatment can help prevent or lower your risk of serious health problems from high blood sugar levels. These include sight loss, toe or leg amputations, kidney disease, heart attack and stroke.   

So it's important to get all of your health checks. See below the most common diabetes heath checks people miss out on - and tips to make sure you get them.

Diabetes health checks people are more likely to miss out on  

People are less likely to have their urine check for kidney disease, eye check and foot check than the other diabetes health checks.  

It can be difficult to access your annual review or diabetes health checks appointments – but as routine NHS care, it’s something that GPs and hospital teams should have set aside time for. So don’t feel guilty about chasing up appointments. They are there to help you and your team monitor how diabetes is affecting other parts of your body and help keep you healthy.  

There are also other reasons why people may not get these health checks. Find out some of these reasons and see our tips to help you get these checks: 

Providing a urine sample to check for kidney disease

Lots of people miss out on this check because providing a sample of your wee isn’t always easy. 

You might be sent a bottle to wee into at home, or have to provide a sample on the day of the appointment. Some people find this stressful but also a bit messy. Equally, carrying around a urine sample all day if you’re going to work isn’t practical.  

Tips to make providing a urine sample easier 

Ask the healthcare professional doing the check for flexibility. If you need something bigger to wee into or if you’d rather take the bottle home, do ask.  

You should also make sure the lid is on safely and could try wrapping tissue around the sample bottle or putting it into sealed bag if you are worried about it spilling.  

Sally, who has type 2 diabetes: "I don't want to carry the urine sample around in my bag at work all day, so I do it at the surgery. I've started using the toilet they have upstairs so I don’t have to walk through the waiting room with it."

Getting a diabetic eye check 

Lots of people miss out on this check because the diabetic eye check appointment is usually done at different clinic and not at your GP surgery or hospital.  

So, you may feel uncomfortable seeing someone new, or having to travel to a place you don’t know.  Some people may also worry about the results of the eye check more than other tests.  

You also won’t be able to drive after your appointment as you’re often given eye drops to help make the photo of your eyes clearer, which can make them blurry for a while afterwards. 

But it is important to get this check to see if diabetes is affecting your eyes so you can get treatment to delay or prevent it affecting your sight.  

Tips for making sure you get a diabetic eye check 

Remember that this isn’t a sight test, so you won’t have the expense of buying new glasses, if this is worrying you. 

It’s important to think about how to get to and from your appointment especially as you won’t be able to drive afterwards. If the appointment is hard to get to by public transport, check with the eye check provider or GP if there are other clinics that may be easier to get to even if they're further away. 

And if you’re unsure about the check itself or going to a new place, ask a neighbour, friend or relative to go with you.  

If you aren’t getting diabetic eye check appointments, you should contact your GP or hospital team. They can refer you to your nearest eye check service. If you are housebound, you should ask them how you can access these appointments in a way that’s accessible to you.

"Having my eyes checked prevented me losing my sight as problems with a build-up of fluid around my retina and issues with my blood vessels were caught early. I was able to get treatment before any lasting damage.

James Baillie, who has type 1 diabetes 

Getting a foot check  

Sometimes there may not be enough time at your annual review appointment for a foot check to be done. And sometimes you may worry about your feet not being as clean or smelling as you’d like.  

Tips for making sure your feet are checked

If there isn’t time for a foot check, do insist on a follow-up appointment. It isn’t enough for you to have checked them yourself. 

If you’re worried about someone touching your feet remember the person checking your feet is a trained professional and has seen it all and they will not mind.   

When you attend appointments, it can speed things up if you wear something that’s quick and easy to take off and put back on. So, for example wear socks instead of tights and shoes that are easy to remove.   

“The GP asks if I’ve noticed any changes in my feet, if I say no, they don’t check them. So unlike the blood test results, I don’t feel confident that there aren’t any problems. I feel too embarrassed to ask if they can do a foot check,” John, who has type 2 diabetes.

Other possible reasons people may not get their diabetes health checks

Having to repeat the checks 

Sometimes it can be frustrating if you are asked to have the same checks at a hospital diabetes service and at your GPs.  

To stop this happening, if your check-ups are done by your hospital team, you’ll need to ask your hospital team to send the information to your GP. And ask your GP to add any test results from the hospital to your records. 

Fear of being judged 

If you don’t get on with your healthcare professional – or feel they judge you, then it can be difficult to attend your appointments. Ask if it is possible to see a different healthcare professional for your diabetes health checks. If that’s not possible, but your relationship with the person doing the checks is preventing you from going, then think about whether you want to change your GP or diabetes team. 

Worry about starting medication  

The thought of having to start medication for diabetes can be worrying for some people, especially if they have read about the side effects. But there are now several different types of medications for type 2 diabetes so if you are having side effects or don't like how the medication is making you feel, you should talk to your diabetes team about what medications may be best for you.

Prioritising other things above your health   

It can be hard to make time for your health checks, especially if you are not sure why they are important. Busy lives can mean you prioritise work, family or other life pressures. But we know that diabetes related health problems can come on quicker in younger people so it’s important to take time out to make sure your health is being looked after.  

What other diabetes care should I be getting? 

If you have diabetes, there is other NHS care available if you need or want it. There are also certain checks and appointments that you should have when you're first diagnosed - see below. 

We've also got lots of information about the NHS care to expect when you have gestational diabetes. 

NHS care to expect when you’re first diagnosed 

Everyone living with diabetes should have certain checks and appointments when they’re first diagnosed with diabetes, to make sure you understand your condition and can live well with diabetes. If you didn’t have any of these when you were first diagnosed, speak to your healthcare team. 

Everyone living with type 1 or type 2 diabetes should have: 

  • A full assessment of your medical history, and anything going on in your personal life that might affect your diabetes.  

  • A referral to a diabetes group education programme that works for you and your cultural background, or the same type of education in a one-to-one appointment if you prefer. This should be within a year of diagnosis if you live with type 1 diabetes.

  • Information about the medical exemption form for free prescriptions if you live in England. You don’t need this in Northern Ireland, Scotland, and Wales as prescriptions are free for everyone. 

Within six months of being diagnosed with type 1 diabetes, you should have: 

  • An individual diabetes management plan, discussed and agreed on with your healthcare team, that works for you and your cultural background, including your personal targets, contact details for your diabetes team and follow-up plans. 

  • Detailed information on how to live well with type 1 diabetes including giving your insulin, counting carbohydrates, managing hypos, managing when you’re ill, physical activity, and DVLA requirements for driving. 

  • A review with a dietitian.  

  • Your antibodies measured to confirm your diagnosis if it’s not clear what type of diabetes you have. 

When you’re diagnosed with type 2 diabetes, you should have:  

  • If it’s right for you, a discussion about weight management or weight loss and type 2 diabetes remission, which is when your average blood sugar levels are no longer in the range for diabetes and you don’t need medication. 

  • A review of your emotional wellbeing and mental health needs. 

  • A review of your medication. 

  • A summary of your agreed diabetes management plan and when it should be reviewed again.    

NHS care to expect if you need it 

There are some diabetes checks and appointments that you should have access to but not everyone will need. Speak to your healthcare team if you think you need any of this help but aren’t getting it.  

Everyone with diabetes should have access to: 

  • An HbA1c check every three to six months if you’re struggling to meet your targets.

  • The chance to meet and get support from other people living with diabetes. 

  • Good quality care with access to diabetes specialists if you’re in hospital, including access to mental health support if needed. 

  • Pre-pregnancy review if you’re planning to have a baby, and advice from specialists at least 12 weeks before stopping contraception. 

  • Regular reviews at least every two weeks by the diabetes team during pregnancy. 

  • Support with sexual health concerns.  

  • A review of your emotional health and wellbeing needs. 

  • A review and update of your management plan. 

  • Appointments in a way that you prefer, whether that’s by phone or face to face, or reviewing your blood sugar levels with your healthcare team online, for example. 

  • Specialists who can help you manage any diabetes complications.  

Everyone living with type 1 diabetes should have access to: 

  • A review of the diabetes knowledge you already have and would like to have,  

  • Advice about your diet from a dietitian. 

  • A thyroid function blood test. 

  • A chat about diabetes technology offered locally that could help you. This includes continuous or flash glucose monitoring, which everyone should have access to if they would like it, or an insulin pump if you are not meeting your targets. 

  • Support from specialists who can help you manage your medication and blood sugars around physical activity.  

Everyone living with type 2 diabetes should have access to: 

  • Support to lose weight if you want or need to. 

  • Advice on physical activity. 

  • Technology to monitor your blood sugar levels, like a continuous glucose monitor, depending on certain criteria. 

You will also have access to other NHS care that is still important for your diabetes management, like flu and Covid-19 vaccines, screening services for other conditions, help to give up smoking, weight management support, and dental care 

Some areas offer other opportunities to improve your general health and diabetes wellbeing, like weight management, organised physical activity and active community groups. Ask your healthcare team what other support is available to you. 

https://www.diabetes.org.uk/guide-to-diabetes/managing-your-diabetes/care-to-expect?utm_campaign=1180083_General%20Enewsletter%20June%202024&utm_medium=email&utm_source=dot_digital&utm_content=X6CSTXD%20-%202024%20June%20eNewsletter%20EM%20%20%20%20%20%20%20%20%20%20%20%20%20%20%20%20%20%20%20%20%20%20ELRT&dm_i=79RZ,PAK3,1PBE5R,3CZGB,1

Diabetes diet: 6 diets to control your blood sugar levels

From healthshots.com

Managing diabetes includes more than just eating at regular intervals. Prioritising healthy eating is vital. Here are 6 nutritious diets for diabetes that can help manage blood sugar levels 

Managing diabetes requires a comprehensive approach, with diet playing a crucial role. A healthy diet helps regulate blood sugar levels, maintain a healthy weight, and prevent complications associated with unbalanced blood sugar levels. If you have diabetes, your diet should be high in fibre, low in unhealthy fats, and rich in essential vitamins and minerals. By focusing on whole, minimally processed foods, you can have better control over your blood glucose levels. Gear up as we bring you some expert-recommended healthy diets for diabetes!

Best diets for diabetes

Here are 6 healthy diet plans that people with diabetes can follow to manage sudden spikes in their blood sugar levels:

1. Mediterranean diet

Renowned for its heart-healthy benefits, the Mediterranean diet is packed with essential vitamins, minerals, and antioxidants. Since it is rich in fibre and antioxidants, it helps regulate blood sugar levels and promote heart health, making it ideal for diabetes management. It focuses on foods such as fruits, vegetables, whole grains such as quinoa, barley, and whole wheat, healthy fats such as olive oil, nuts, and seeds, and lean proteins such as fish, poultry, and legumes. These foods can improve insulin sensitivity and reduce inflammation, making it an excellent choice for diabetes management.

2. Low-carbohydrate diet

By reducing the intake of high carbohydrate foods like bread, pasta, and sugary snacks, you can effectively regulate blood sugar levels in people with diabetes. A study published by Frontiers in Nutrition finds that a low carbohydrate diet can stabilise glucose levels, managing diabetes. This diet includes foods such as:

  • Non-starchy vegetables such as broccoli, spinach, and peppers
  • High-protein foods such as eggs, lean meats, and tofu
  • Healthy fats such as avocados, nuts, and olive oil
                                              A high-carb diet may raise sugar levels. Image courtesy: Adobe Stock

3. DASH diet

Unlike fad diets that are hard to maintain, the DASH (Dietary Approaches to Stop Hypertension) diet is easy to start and follow. Originally designed to combat high blood pressure, this can also benefit those with diabetes. Since people with diabetes have a higher risk of developing hypertension than people without diabetes, this diet can be very beneficial, finds a study published by the American Diabetes Association. Its focus is on fruits, vegetables, whole grains, and lean proteins that help regulate blood sugar levels and promote heart health.

Make sure you limit salt (sodium intake), and processed foods. Instead add potassium, calcium, and magnesium-rich foods to maintain heart health and reduce sugar from your diet.

4. Plant-based diet

A plant-based diet emphasises foods derived from plants while minimising or eliminating animal products. This diet includes fruits and vegetables, whole grains (such as brown rice, oats, and whole-wheat products), and legumes and nuts (such as beans, lentils, and nuts). These foods may support steady blood sugar levels and offer essential nutrients such as protein and healthy fats.

A study published in the Journal of Geriatric Cardiology found that a plant-based diet can improve insulin sensitivity and reduce the risk of type 2 diabetes. This diet is also known to promote heart health, aid in weight loss and improve gut health.

5. Paleo diet

The paleo diet, also known as the paleolithic diet, focuses on foods presumed to have been available to our ancestors. While it is not clear what our ancestors consumed across the globe, it is believed that whole foods made up the majority of this diet. It includes:

  • Lean meats and fish, which are high in protein and beneficial omega-3 fatty acids.
  • Fruits such as bananas, avocados, and berries.
  • Vegetables such as broccoli, carrots, kale, peppers, and tomatoes are rich in vitamins, minerals, and fibre.
  • Nuts and seeds that provide healthy fats and protein.
                                            Paleo diet can help in managing diabetes. Image courtesy: Adobe Stock

This diet does not include processed foods, sugars, and grains, which can make it tough to manage blood sugar levels. Compared to other diets, the paleo diet resulted in lowering the risk of sudden blood pressure, weight gain, and high blood sugar levels, according to a study published by the Journal of Diabetes Science and Technology.

6. Low-glycaemic index diet

The foods low in glycaemic index (GI) foods can have an impact on blood sugar levels. A low glycaemic index diet involves swapping foods high in GI, to minimise the risk of sudden spikes in blood glucose levels, making them beneficial for diabetes management. Overall, this diet can help reduce blood sugar levels and lower the risk of heart disease, type 2 diabetes, and weight loss. Low-GI foods include green vegetables, legumes, fruits, kidney beans, raw carrots, lentils, and whole grains, to minimize spikes in blood glucose levels, making them beneficial for diabetes management.

Foods to avoid with diabetes

People with diabetes should avoid certain foods that can cause blood sugar spikes and negatively impact their overall health. Here are 7 foods to avoid if you have diabetes:

1. Avoid sugary drinks such as sodas, sweetened juices, and energy drinks, which are high in sugar and can cause rapid blood sugar spikes.
2. Refined carbohydrates such as white bread, pasta, and pastries lack fibre and can quickly raise blood glucose levels.
3. High-sugar snacks like candy, cookies, and other sweets that are high in sugar and low in nutritional value should also be avoided.
4. Fried foods, including french fries, fried chicken, and other deep-fried items, are high in unhealthy fats and calories. So, avoid them as well.
5. Excessive consumption of alcohol with diabetes can lead to unstable blood sugar levels and other health complications.
6. High-fat dairy products like full-fat milk, cheese, and cream can contribute to insulin resistance, so avoid them.

Keep a check on your regular diet in order to manage diabetes!

https://www.healthshots.com/healthy-eating/nutrition/healthy-diabetes-diet/

Saturday, 8 June 2024

Oral insulin drops under the tongue could replace diabetes injections

From newatlas.com

Diabetics sick of daily injections may have renewed hope for a less invasive alternative. Scientists at the University of British Columbia (UBC) have developed a new delivery method for insulin where users just place a few drops under their tongue.

       
Drops of insulin placed under the tongue could be a new alternative to injections for diabetics   Deposit photos 

A hallmark of diabetes is the inability to produce enough insulin to regulate blood glucose levels. Those with type 1, and many with type 2, will need insulin a few times a day, and that’s usually delivered through a subcutaneous injection. Not only is that uncomfortable, but it can be hard for patients to stick to, and creates potential biohazard waste.

Less invasive methods are in development, with varying levels of success. Experimental techniques include controllable implants, or ultrasound patches that deliver drugs straight through the skin, but the major avenue of research is oral insulin delivery. After all, popping a pill is simple, painless and something many people already do everyday.

But again, there’s a few problems with that, too. Insulin is a fragile molecule that doesn’t survive the journey through the stomach to the intestines, where it can be absorbed into the bloodstream. Encapsulating it in different materials can help, or even making capsules that physically inject it into the lining, but going this way means insulin is first metabolized through the liver, which can change its structure.

For the new study, the UBC team developed a new system that might still be called oral insulin. Instead of being swallowed though, it takes the form of drops placed under the tongue. This method, known as sublingual administration, is useful for drugs that don’t survive the stomach. It’s effective because the tissue under the tongue contains a lot of capillaries, allowing the drug to quickly diffuse into the bloodstream.

Normally, this method wouldn’t work well for insulin because it’s a large molecule that can’t easily get through cells. So the team paired it with a cell-penetrating peptide (CPP), made from fish byproducts, that makes cells more porous.

“Think of it as a guide that helps insulin navigate through a maze to reach the bloodstream quickly,” said Dr. Jiamin Wu, a researcher on the study. “This guide finds the best routes, making it easier for insulin to get where it needs to go.”

The team tested the technique in mice. When paired with CPP, the insulin successfully reached the bloodstream and controlled blood glucose levels about as well as insulin delivered via injection. Without the guide peptide, the insulin tended to get stuck in the lining of the mouth.

The researchers are currently working on licensing the technology to commercial partners. The system was described in two recent papers published in the Journal of Controlled Release.

https://newatlas.com/medical/oral-insulin-drops-tongue-diabetes-injections/

Friday, 7 June 2024

Timing is key for type 2 diabetes drug performance

From newswise.com

Newswise — Researchers from the University of Adelaide could be closer to discovering a better way to use metformin, a common type 2 diabetes medication.

Metformin, which has been a cornerstone in diabetes treatment since the 1960s, is typically taken with meals to reduce gastrointestinal side effects but new research is suggesting patients could see improved results if it’s taken before meals.

Dr Cong Xie postdoctoral research fellow in the Centre of Research Excellence in Translating Nutritional Science to Good Health, at Adelaide Medical School, worked with Associate Professor Tongzhi Wu and a team which studied the gastrointestinal effects of the drug on 16 people living with type 2 diabetes who were already using it to treat the condition.

Their findings were published in the journal Diabetologia and are now being used in e-learning by the European Association for the Study of Diabetes (one of the largest international platforms for diabetes research and clinical practice).

“Our results demonstrate administering metformin 30 to 60 minutes before a meal reduces plasma glucose levels while increasing the secretion of the incretin hormone glucagon-like peptide 1 (GLP-1) and insulin levels,” Dr Xie said.

“GLP-1 is a hormone secreted from the gut, which exhibits several actions, including the suppression of appetite, stimulation of insulin, slowing of gastric emptying and the subsequent glucose absorption in the intestine, all of which are beneficial for the control of blood sugar and body weight.

“A number of GLP-1-based drugs are now used clinically for the management of obesity and type 2 diabetes; these drugs also reduce the risk of cardiovascular disease.”

Dr Xie said the plasma GLP-1 levels increased only when metformin was given before the subjects were given a glucose infusion and not at the same time.

“This suggests the levels are affected by changes in the glucose-gut interaction,” he said.

Associate Professor Wu said the study found there was no real difference to the nausea scores of patients between the administration times.

“The findings of our study suggest that the empirical recommendation for ingestion of metformin with meals may have compromised its efficacy to improve blood glucose control after meals,” he said.

“Modification of the timing of metformin ingestion in relation to meals could be a cost-effective approach to improve glycaemic control in people living with type 2 diabetes.”

“We are now planning to extend this research in a real-world setting to examine whether administration of metformin before meals will lead to better blood glucose control in people with type 2 diabetes in the long term.”

https://www.newswise.com/articles/timing-key-for-type-2-diabetes-drug-performance 

Tuesday, 4 June 2024

4 Things to Know about Type 1 Diabetes

From managedhealthcareexecutive.com

  • Type 1 diabetes is an autoimmune disease. In type 1 diabetes, the pancreas does not make insulin. In 1974, two studies published here and here in The Lancet highlighted research that showed how type-1 diabetes is associated with the development of antibodies directed against insulin-producing beta cells in the pancreas.
  • Type 1 diabetes has three stages: stage 1, where patients are pre-symptomatic with normal blood glucose levels; stage 2, where patients are pre-symptomatic but have developed glucose intolerance; and stage 3, where patients develop symptoms that include increased hunger and thirst, blurry vision, fatigue, and diabetic ketoacidosis, a complication in which acids build up in the blood.
  • In 2021, 38.4 million Americans had diabetes. Of these, 2 million had type 1 diabetes, including about 304,000 children, according to the CDC. About 1.7 million adults aged 20 years and older reported having type 1 diabetes and are using insulin. Between 2002 and 2018, the overall incidence of type 1 diabetes increased significantly. Non-Hispanic Asian or Pacific Islander children and adolescents has the largest significant increases in incidence of type 1 diabetes but non-Hispanic White children and adolescents had the highest overall incidence of type diabetes
  • A large retrospective study published in the Journal of Managed Care & Specialty Pharmacy in 2020 of paediatric and adult patients with type 1 diabetes showed that overall medical costs averaged about $1,500 per patient per month, and diabetes-related costs totalled almost $800 per patient per month. Pharmacy costs contributed to more than half of the monthly diabetes related costs.

Monday, 3 June 2024

Next step in diabetes care: Use CGM data to inform treatment decisions

From healio.com

Key takeaways:

  • CGM has changed the way providers assess glycaemic control for people with diabetes.
  • Providers and patients will both have a role in using CGM to manage diabetes and make treatment decisions in the future.

BOSTON — Continuous glucose monitoring has transformed the field of diabetes over the past 25 years. The technology can be used by both providers and people with diabetes to improve disease management, according to a speaker at ENDO 2024.

Richard M. Bergenstal, MD, executive director of the International Diabetes Centre, HealthPartners Institute in Minneapolis, detailed the history of CGM in the conference’s 2024 Clark T. Sawin Memorial History of Endocrinology Lecture. Bergenstal cited CGM and other diabetes devices as playing a pivotal role in the improvement in diabetes management during the 21st century. However, he said providers must continue to improve their implementation of CGM and effectively use the data from the devices in their management of diabetes.

Diabetes_Smart_Phone_Adobe_330248340
Advances in CGM allow both patients and providers to analyse data and make diabetes management decisions. Image: Adobe Stock

“We have decades of comfort with the HbA1c. That’s good, that’s an incredible marker of your risk,” Bergenstal said during the Clark T. Sawin Memorial History of Endocrinology Lecture. “But I want to get across this bridge ... to get clinicians comfortable with using time in range and time below range to adjust therapy and change management as opposed to just assessing.”

History of CGM

This year marks the 25th anniversary of the FDA approval of the first CGM device. In 1999, the Medtronic MiniMed was approved by the FDA for people with diabetes. This was followed by the approval of the GlucoWatch Biographer in 2001. Bergenstal cited these approvals as the first step on his roadmap of the effective use of CGM, which was published in Diabetes Spectrum in 2023.

Richard M. Bergenstal

From 2006 to 2014, CGM progressed in several ways, according to Bergenstal. The devices became more accurate and no longer required calibration. They became nonadjunctive and more interoperative. A major step forward occurred in 2012, when the International Diabetes Centre and Helmsley Charitable Trust partnered to convene a panel of diabetes experts to standardize CGM metrics. The panel’s findings led to the creation of CGM targets, including time in range encompassing a glycaemic level of 70 mg/dL to 180 mg/dL. The panel also determined people with diabetes should try to achieve a time in range of more than 70%.

The number of CGM trials conducted expanded immensely in the late 2000s and through the 2010s. A systematic review and meta-analysis of 15 trials, published in Diabetes Care in 2020, found CGM improved time in range and decreased time above range, time below range and glucose variability for people with type 1 or type 2 diabetes. Additionally, results from the REPLACE trial, published in Diabetes Therapy in 2017, found that use of flash CGM lowered hypoglycaemia by 43% more than self-monitoring blood glucose.

The integration of CGM with insulin pumps and insulin pens was another milestone in diabetes management. Bergenstal credited Aaron J. Kowalski, PhD, for publishing a roadmap for the use of automated insulin delivery that paved the way for CGM to be integrated with multiple types of devices.

“We’re in the era now of starting to mix and match,” Bergenstal said. “Some companies will [integrate] with them all, some will pick just one piece of this.”

Using CGM

With more data and more device approvals, providers have begun looking at CGM metrics to inform treatment decisions. Bergenstal noted that the American Diabetes Association changed its assessment of glycaemic control recommendation in the 2021 Standards of Care to allow other glycaemic measurements outside of HbA1c. The recommendations were further updated to specify the use of time in range or glucose management indicator for glycaemic assessment.

“Now is the time to really put [CGM] into action,” Bergenstal said.

Bergenstal said providers can take a two-pronged approach to diabetes management. With real-time data and integrated devices, people with diabetes can review their glycaemic status and make treatment adjustments. Additionally, providers can review data retrospectively through the cloud or electronic health records and make further adjustments.

In a study published in Diabetologia in 2024, researchers randomly assigned adults with type 2 diabetes, 1:1:1, to a CGM intervention group that was taught to use data to make insulin dose and timing adjustments, a conventional group using integrated CGM without additional education, or a control group not using CGM. Researchers found the intervention group had a greater HbA1c reduction than the other groups.

More CGM innovations are still to come, according to Bergenstal. Expanded indications for CGM use during pregnancy, in the hospital, by people with type 2 diabetes who do not use insulin and by those with prediabetes are on the horizon. Future diabetes devices may include CGM with continuous ketone monitors, non-invasive CGMs and smartwatches that can act as a CGM. Additionally, AI will have an even greater role.

“There’s data in the [ambulatory glucose profile] that can guide decisions for the best drugs to use, lifestyle choices and other risk factors,” Bergenstal said. “We’re looking forward to AI helping us look at patterns.”

https://www.healio.com/news/endocrinology/20240602/next-step-in-diabetes-care-use-cgm-data-to-inform-treatment-decisions 

Saturday, 1 June 2024

Three early signs of Type 2 diabetes you should be on the look out for

From msn.com

There is a chance that you could have Type 2 diabetes without being aware of it, so looking out for these three early signs could be your best bet.

The reason behind this is that some of the symptoms do not necessarily make you feel unwell, so you may not associate them with being sick. 

Here are three symptoms that you should keep an eye out for if you're in any way concerned you may be at risk of developing Type 2 diabetes.

The Health Service Executive in Ireland has listed a number of symptoms that you could show signs of Type 2 diabetes.

  • feeling thirsty all the time - drinking excessive amounts of liquids or unable to quench your thirst
  • peeing more than usual, particularly at night
  • feeling tired, lack of energy, sleeping more than usual

They also said to be wary of losing weight without trying to, which is in fact a sign of a number of other sicknesses, so that in particular is a concerning sign.

There are also a number of people who may be most at risk of developing Type 2 diabetes, including people over the age of 45, obese people, or those with a family member who has diabetes.

This list includes:

  • are physically inactive - for example, if you take less than 30 minutes of physical activity most days
  • have high blood pressure, high cholesterol, low HDL cholesterol or high triglycerides
  • have a history of heart disease
  • have a medical condition that requires long-term steroid use