Wednesday 31 January 2024

Weight loss in people with type 2 diabetes can change cancer-related proteins

From news-medical.net

A weight loss intervention in people with type 2 diabetes was found to alter levels of cancer-related proteins, according to the findings of a new University of Bristol-led study. The study, published in eBioMedicine, is the first to show that weight loss in people recently diagnosed with diabetes can change the levels of cancer-related chemicals circulating in the blood.

According to Diabetes UK, over five million people in the UK live with diabetes and over 600 million people could be afflicted worldwide by 2045. Weight loss is now a key intervention thanks to the Diabetes Remission Clinical Trial (DiRECT), which found a dietary weight loss program could put type 2 diabetes into remission.

Despite this positive development, individuals with type 2 diabetes face an increased risk of developing several types of cancer. Previous studies have found that having increased body weight alters the levels of circulating proteins with a known link to cancer. Motivated by these findings, researchers from Bristol Medical School collaborated with colleagues from the universities of Glasgow and Newcastle who led the DiRECT trial. They sought to evaluate whether the benefits of weight loss in people with type 2 diabetes also impacts their risk of developing cancer.

To investigate this, the team used data from 261 patients with type 2 diabetes who were enrolled in the DiRECT trial. The team analysed their blood samples from before and after weight loss to find out if proteins known to be related to cancer were altered by the weight loss intervention.

Nine cancer-related proteins in blood samples were found to be changed by the weight loss intervention compared with the control group who had received standard care for diabetes treatment.

Results from this study help us gain insight into potential mechanisms linking type 2 diabetes and body fatness with cancer development. These findings offer encouraging evidence that the increased cancer risk seen in people with diabetes might be reduced with weight loss interventions. This has important implications for both diabetes treatment and cancer prevention.

The next step for this research is to find out whether the short-term changes we identified really do result in longer-term reduction in cancer risk in people with diabetes."

Emma Hazelwood, one of the study's lead authors from the University of Bristol's MRC Integrative Epidemiology Unit (MRC IEU)

The study was funded by Diabetes UK, Cancer Research UK, World Cancer Research Fund, and Wellcome.

https://www.news-medical.net/news/20240130/Weight-loss-in-people-with-type-2-diabetes-can-change-cancer-related-proteins.aspx 

Tuesday 30 January 2024

Diabetes and Hydration: Are You Drinking Enough Water?

From diatribe.org

Do people with diabetes have special hydration requirements? Here’s how water affects blood sugar – plus tips for getting more much-needed fluids.

Between carrying a water bottle around and fitness apps reminding you to hydrate, there’s no reason you shouldn’t be elevating your water game. In the past few years, there’s been more focus on consuming water, which is a great (and necessary) habit to incorporate. 

Drinking enough water has many benefits, including improved circulation and digestion. Our bodies are made up of mostly water. Adequate hydration is essential to most of the systems in our body. Furthermore, it’s especially significant for people with diabetes. 

“Those with diabetes don't necessarily need more water than those without, but hydration is even more important for those with diabetes,” said Amanda Lane, a certified diabetes care and education specialist. 

Here’s why hydration is so critical for blood sugar and your overall health.

What’s the ideal amount to drink?

You may have heard that you need to drink eight glasses of water every day. It turns out, there isn’t a hard and fast rule when it comes to how much. 

“Water needs vary from individual to individual. Needs are based on age, medical conditions, activity, where you live (if it’s a hot or cold environment), and if you are pregnant or breastfeeding,” said Amy Beney, a certified diabetes care and education specialist.

General recommendations can be used as a starting point. According to the U.S. National Academies of Sciences, Engineering, and Medicine, an adequate daily fluid intake is:

  • About 15.5 cups (3.7 liters) of fluids a day for men

  • About 11.5 cups (2.7 liters) of fluids a day for women

Keep in mind that these recommendations also include foods and other beverages that contain water. For example, foods like soup and yogurt have quite a bit of water.

So how do you know how much to drink? Esther Tambe, a registered dietitian nutritionist and certified diabetes care and education specialist, shared an easy method.

“One way to determine if you are adequately hydrated is to do a urine colour check. The colour of your urine can indicate your hydration status; a light, pale yellow colour suggests adequate hydration,” Tambe said.

That said, she added this simple strategy may not be the best indicator for everyone as other factors like medications, vitamins, and certain foods can change the colour of your urine. Liver and kidney disease can also alter your urine color.

Is drinking when thirsty enough?

Thirst is a sensation that occurs in response to a reduction in fluid in the body’s cells. So while you may be slightly dehydrated when you start to feel thirst, this is a normal reaction.

In most situations, drinking to quench your thirst is usually enough to properly hydrate. However, if you are participating in endurance or high-intensity physical activity, you may need to plan to ensure you’re getting enough fluids. 

In some cases, like in older populations, thirst may be diminished making it essential for more regular and intentional hydration.

Diabetes and dehydration

Your body is constantly using and losing fluid. Dehydration, or not drinking enough fluids, can increase your blood sugar. 

“When dehydrated, your blood becomes more concentrated with glucose,” Tambe said.

Research has shown that inadequate fluid intake is associated with hyperglycaemia or high blood sugar. Constantly being in a dehydrated state is also not good for metabolic health in general.

Additionally, elevated blood glucose levels may increase  the electrolytes in your blood, thereby disturbing fluid balance. Beney further described how diabetes can cause dehydration.

“When blood sugar is high, the body attempts to get rid of the glucose by producing more urine. This can also create dehydration in the body due to increased urine production,” said Beney.

While you may not require more water than someone without diabetes, you may have to put in more effort to avoid dehydration.

Signs of dehydration

“Signs of dehydration can be tricky since they aren't specific,” said Lane. 

That’s because many symptoms of dehydration overlap with the signs of high blood sugar. Signs of dehydration to watch out for include: 

  • Headache

  • Dizziness or light-headedness

  • Muscle cramping

  • Dark, smelly urine

  • Increased thirst

  • Fatigue

  • Nausea

  • Salt cravings

“Prolonged dehydration can even cause skin tenting and slow wound healing,” she added. 

Does drinking water lower your blood sugar?

There’s a reason you’re thirsty when your blood sugars are above target.  

“Water can lower blood sugar levels slightly. Properly working kidneys naturally filter out some of the extra glucose, and being hydrated helps the kidneys work at their best,” Lane explained

Tips for getting enough fluids

How do you prioritize your hydration? Here are some tips for boosting your fluid intake:

1. Start with water:  Beney suggested drinking a glass of water first thing in the morning. “One tip I use myself is that I fill my coffee mug with water and do not start drinking coffee until my water is gone.”

2. Keep water accessible: “Keep a water bottle in your car, workstation, or bag,” Beney said. “If it’s in your visual field, you may be more tempted to drink.”A man drinks from a water bottle

3. Use a reminder: Technology to the rescue. There are tons of apps you can use to remind you to drink up. Tracking your water intake in a fitness app, journal, or planner can also be satisfying and motivating.

4. Get a bottle you like: Lane suggested using clear bottles so you can see how much you’ve consumed or how much you have left.” Insulated, stainless steel water bottles are also nice for keeping water nice and cold, if that’s what you prefer.

5. Create a habit: Build the habit of drinking water by pairing it with another activity, like after you brush your teeth or when you take medications.

6. Use a straw: “You tend to drink more using a straw than sipping from a cup,” Beney said. Nowadays there are lots of options for metal or reusable straws to avoid waste.

7. Pair a beverage with your food: “Always have something to drink when you eat. Pour yourself a glass of water when you sit for a meal,” said Beney.

8. Drink early: Don’t want to be up going to the bathroom all night? Tambe suggested consuming water earlier in the day and cutting off liquids 3-4 hours before bed.

What if you don’t like water?

Some people just don’t like drinking water. No worries – you can still be adequately hydrated with these tips: 

  • Flavoured water: “Try infusing water by adding fruit slices to improve the taste,” Tambe recommended. Remember that store-bought infused water generally contains some calories, sugar, and carbs because extra ingredients are often added during manufacturing. It’s always a good idea to check nutrition labels before consumption.A glass of flavored water

  • Sparkling water: Change it up and add in a can of your favourite sparkling water to up your fluid intake.

  • Herbal teas: Tea offers health benefits like bolstering the immune system and warding off inflammation. There are also so many different flavours and types of herbal tea it’s a great way to diversify your beverage options.

  • Other beverages: Don’t forget milk, which also provides other nutrients, like protein and vitamin D. However, milk contains lactose, a sugar naturally found in milk. It’s important to keep in mind that even non-dairy milks like oat milk often contain added sugar. There are also prebiotic sodas as an alternative to sugary soft drinks (again, they still have “natural” sweeteners, which may be healthy but still contribute to sugar intake). While too much caffeine may leave you feeling jittery and affect your blood sugar, beverages like green tea and coffee still count toward your fluid intake. Caffeine-free tea and coffee are also available if caffeine is a problem for you.

The bottom line

Being dehydrated can increase your blood sugar levels. High blood sugar can also cause you to become dehydrated. Water needs are different for everyone and critical for all of your body’s functions. Be purposeful about your fluid intake to be sure your body is working at its best. 

https://diatribe.org/diabetes-and-hydration-are-you-drinking-enough-water

Sunday 28 January 2024

Understanding Prediabetes: The Borderline Zone of Diabetes Risk

From metropolisindia.com

Prediabetes is an often overlooked transitional phase between health and the risk of diabetes. Most people are unaware of this condition as its symptoms are often not noticeable. Therefore, in this guide, learn everything you need to know about prediabetes, understand the implications, risk factors, and, most importantly, effective strategies to manage and prevent its progression. So, read on!

What is Prediabetes?

Prediabetes is a health condition in which your blood sugar levels are higher than normal but not yet high enough to be diagnosed as Type 2 diabetes. It serves as a warning sign, indicating an increased risk of developing diabetes, cardiovascular diseases, and several other disorders like nephropathy, neuropathy, etc., as you exhibit insulin resistance, wherein your body's cells do not respond effectively to insulin.

The normal fasting glucose level is usually between 70 and 99 milligrams per decilitre (mg/dL). A fasting blood sugar level between 100 and 125 mg/dL indicates the prediabetic range.


How Common is Prediabetes?

Prediabetes is a very common health condition globally. It is estimated that about 7-8 % of the global adult population will be affected by prediabetes by the year 2045 (close to 587 million individuals). In India, about 10 to 15% of the population suffers from prediabetes. Moreover, many are unaware of their condition, as prediabetes symptoms are not seen in most cases.

What are the Common Symptoms of Prediabetes?

Some common symptoms are:

  • No Symptoms (Asymptomatic): Prediabetes symptoms are often not noticeable symptoms, making regular screenings important for early detection.
  • Increased Thirst and Hunger: You may experience heightened thirst and hunger as a symptom of prediabetes as your body struggles to regulate blood sugar levels.
  • Frequent Urination: Elevated blood sugar can lead to increased urination, which is a common diabetes and prediabetes symptom.
  • Fatigue: Prediabetes symptoms may also include fatigue as you may feel more tired than usual, reflecting the body's struggle with insulin resistance.
  • Blurred Vision: Fluctuating blood sugar levels can affect your eyes, causing temporary blurriness.

What Causes Prediabetes? 

Here are some of the causes of prediabetes:

  • Insulin Resistance: With insulin resistance, your body's cells become less sensitive to the effects of insulin, impairing their ability to absorb glucose from your bloodstream efficiently. As a result, your pancreas compensates by producing more insulin in an attempt to lower blood sugar levels. However, over time, this increased demand on the pancreas can exhaust its capacity to produce sufficient amounts of insulin, leading to persistently high blood sugar levels.
  • Increased Metabolic Disturbance: One consequence of high blood sugar is increased oxidative stress, which occurs when there is an imbalance between the production of Reactive Oxygen Species (ROS) and your body's ability to neutralise them with antioxidants. Over time, this oxidative stress contributes to the development and progression of various complications associated with diabetes, including cardiovascular disease, kidney dysfunction, and nerve damage.

What are the Risk Factors for Prediabetes?

Some of the risk factors for prediabetes are:

  • Age: The risk of prediabetes increases with age, particularly after 45.
  • Family History: A family history of diabetes raises the likelihood of prediabetes, suggesting a genetic predisposition.
  • Obesity: Excess body weight, especially abdominal fat, is a significant risk factor, often leading to insulin resistance. It can also be a symptom of prediabetes.
  • Physical Inactivity: Lack of regular exercise contributes to weight gain and insulin resistance.
  • Unhealthy Diet: Diets high in refined sugars, carbohydrates, and saturated fats contribute to insulin resistance and prediabetes.
  • Gestational Diabetes: Women who had gestational diabetes during pregnancy are at an increased risk.
  • Polycystic Ovary Syndrome (PCOS): Women with PCOS are at a higher risk of prediabetes.
  • Hypertension: High blood pressure is often associated with insulin resistance and prediabetes.
  • Sleep Disorders: Conditions like sleep apnoea can contribute to insulin resistance and increase your prediabetic glucose levels.
  • Stress: Chronic stress can contribute to insulin resistance, affecting blood sugar levels and increasing the risk of prediabetes.

What are the Possible Complications of Prediabetes?

Prediabetes poses risks for various health complications if you leave it untreated. The condition increases the likelihood of developing Type 2 diabetes, heart disease, and stroke. Additionally, prediabetes is associated with metabolic syndrome, characterised by elevated blood pressure, abnormal cholesterol levels, and abdominal obesity. These complications escalate the risk of kidney disease, vision problems, and nerve damage in your body.

How is Prediabetes Diagnosed?

Prediabetes is diagnosed through specific blood tests that measure your glucose levels, providing crucial insights into your body's ability to regulate blood sugar. The primary diagnostic tests include:

  • Fasting Blood Sugar Test (FBS): This involves measuring your blood sugar levels after an overnight fast. A reading between 100 and 125 mg/dL indicates prediabetes, signalling impaired glucose regulation in your body.
  • Oral Glucose Tolerance Test (OGTT): After fasting overnight, you consume a glucose-rich solution. Your blood sugar levels are then tested two hours later. Readings between 140 and 199 mg/dL suggest prediabetic glucose levels, indicating your body's struggle to manage glucose effectively.
  • Haemoglobin A1c Test: This test provides a comprehensive view of average blood sugar levels over the past two to three months. An A1c level between 5.7% and 6.4% is indicative of prediabetes

How Can I Reverse Prediabetes?

Reversing prediabetes involves making significant lifestyle changes to improve your insulin sensitivity and blood sugar regulation. Here are key steps that may help in reversing prediabetes:

  • Balanced Diet: Focus on a well-balanced diet for prediabetes that includes a variety of whole foods such as fruits, vegetables, lean proteins, whole grains, and healthy fats. Limit the intake of processed foods, sugary snacks, and refined carbohydrates.
  • Portion Control: Be mindful of portion sizes to avoid overeating and maintain a healthy weight.
  • Exercise Routine: Engage in regular physical activity, aiming for at least 150 minutes of moderate-intensity aerobic exercise per week. This can include activities like brisk walking, jogging, cycling, or swimming.
  • Strength Training: Incorporate strength training exercises at least twice a week to build muscle mass, which can enhance insulin sensitivity.
  • Gradual Weight Loss: Aim for gradual and sustainable weight loss if overweight. Losing even a modest amount of weight, such as 5-10% of your total body weight, can significantly improve insulin sensitivity.
  • Consultation with a Nutritionist: Seek guidance from a nutritionist or dietitian to create a personalised prediabetes diet plan that supports weight management and blood sugar control.
  • Hydration and Limiting Sugary Beverages: Stay well-hydrated by drinking plenty of water throughout the day. Limit the consumption of sugary beverages, as they can contribute to blood sugar spikes.
  • Quality Sleep: Ensure you get enough high-quality sleep each night. Poor sleep patterns can affect insulin sensitivity and contribute to the development of prediabetes.
  • Relaxation Techniques: Practice stress-reducing techniques such as meditation, deep breathing exercises, or yoga. Chronic stress can contribute to insulin resistance, so managing stress is crucial for reversing prediabetes.
  • Blood Sugar Checks: Regularly monitor blood sugar levels as your healthcare provider recommends. This helps track progress and ensures early detection of any changes.
  • Sustainable Changes: Aim for lifestyle changes that are sustainable in the long term. Avoid crash diets or extreme exercise regimens, as they may not be maintainable over time. 

Can You Take Medication for Prediabetes?

While lifestyle changes are the primary approach for prediabetes treatment, some doctors may prescribe medications in certain cases. Medication may be considered when lifestyle modifications alone are insufficient for prediabetes treatment. Common medication like metformin helps lower your blood sugar levels.

Can I Prevent Prediabetes?

Yes, you can easily prevent prediabetes through lifestyle changes. Adopt a healthy diet rich in fruits, vegetables, and whole grains, engage in regular physical activity and maintain a healthy weight. You should avoid excessive sugar and processed foods as well as stay away from smoking as much as possible.

What Can I Expect If I Have Prediabetes?

If you have prediabetes, you might struggle to maintain your glucose levels throughout the day. A constant lack of energy while doing normal day-to-day activities is another aspect of having prediabetes. Therefore, once you are diagnosed with prediabetes, it is advisable to meticulously follow a well-rounded lifestyle and avoid foods with a high glycaemic index. This keeping a check on your food intake will reduce the chances of your prediabetes progressing to Type 2 Diabetes.

How Do I Take Care of Myself If I Have Prediabetes?

You can take care of yourself and reverse prediabetes by incorporating healthy habits into your routine. Here's a sample daily plan:

Morning

  1. Breakfast (9 am -10 am)
    • Include a balanced breakfast with whole grains (oatmeal, whole wheat toast), lean protein (eggs, yoghurt), and fruits.
    • Hydrate with water or herbal tea.
  2. Exercise (6 am - 7 am)
    • Engage in 30 minutes of moderate-intensity aerobic exercise, such as brisk walking or cycling.
    • Consider incorporating strength training exercises.

Afternoon

  1. Lunch (1 pm - 2 pm)

Opt for a well-balanced lunch with lean proteins (chicken, fish, tofu), plenty of vegetables, and a small portion of whole grains.

  1. Snack (4 pm -5 pm)

Choose a healthy snack, such as a handful of nuts, greek yoghurt, or raw vegetables.

  1. Stress Management

Take a short break to practice stress-reducing techniques like deep breathing or a brief walk.

Evening

  1. Dinner (8 pm - 9 pm)
    • Consume a dinner rich in vegetables, lean proteins, and a modest serving of whole grains.
    • Avoid heavy, late-night meals.
  2. Post-Dinner Activity
    • Take a short walk or engage in light activity to aid digestion.
    • Avoid excessive screen time before bedtime.

Sleep Hygiene

  • Aim for 7-9 hours of quality sleep.
  • Establish a consistent sleep routine.

Throughout the Day

Hydration

  • Drink plenty of water throughout the day.
  • Limit or avoid sugary beverages.

Weekly

Meal Planning: - Plan and prepare meals ahead for the week, focusing on nutritious options.

Monthly:

  • Health Check-Up: Schedule regular health check-ups to monitor overall health, blood pressure, and cholesterol levels.
  • Education: Stay informed by reading reputable sources or attending educational programs about prediabetes.

When Should I See My Healthcare Provider?

You can consider scheduling an appointment with your healthcare provider if you are experiencing symptoms of prediabetes like increased thirst or frequent urination or if you are losing weight without any physical activity or diet. The American Diabetes Association recommends regular prediabetes/diabetes screening in your 30s or when you see visible symptoms.

What Questions Should I Ask My Healthcare Provider About Prediabetes?

Some of the common questions to ask are:

  • What is my current blood sugar level, and what does it indicate about my prediabetes risk?
  • What lifestyle changes can I make to manage prediabetes effectively?
  • What is my healthy target weight, and how can I achieve it?
  • Should I consider medications to manage prediabetes, and what are their potential benefits and side effects?
  • How often should I monitor my blood sugar levels, and what is the target range?
  • What to eat for prediabetes, and can I consult a nutritionist for personalised advice on a prediabetes diet?
  • What types of exercises are most beneficial for managing prediabetes, and how often should I engage in physical activity?
  • What other health screenings or tests should I undergo regularly?
  • Are there any signs or prediabetic symptoms I should be particularly attentive to?

Conclusion

Managing prediabetes requires you to have a proactive approach involving lifestyle changes and regular monitoring. By adopting a healthy diet, engaging in regular physical activity, and addressing risk factors, you can easily reverse prediabetes and reduce the risk of progression to Type 2 diabetes. Early intervention and education are pivotal for preventing complications associated with prediabetes. 

https://www.metropolisindia.com/blog/prevention-healthcare/understanding-prediabetes-the-borderline-zone-of-diabetes-risk

Friday 26 January 2024

Even Temporary Type 2 Diabetes Remission Brings Huge Long-Term Benefits

From everydayhealth.com

The rate of heart disease and kidney disease goes down long term even if diabetes comes back 

New study results are the first to show that people who can “reverse" type 2 diabetes through intensive lifestyle intervention — even if only temporarily — are less likely to develop heart and kidney disease in later life.

“Reversal” isn’t a medical term; doctors prefer to use the word “remission” (per Everyday Health's network site, Diabetes Daily), which, for type 2 diabetes, is defined as when a person’s A1C — a measure used to monitor blood sugar over a few months — falls below the diabetes range (less than 6.5 percent) without the use of blood sugar–lowering medication.

“There’s a lot of interest in the idea of remission of type 2 diabetes in the news these days. This is the first study to ask the questions ‘What happens after that? What happens after people achieve remission?’” explains lead author Edward W Gregg, PhD, professor at the School of Public Health at Imperial College in London.

“The main takeaway is that lifestyle-based efforts to achieve type 2 diabetes remission are associated with extended health benefits long beyond remission,” Dr. Gregg says.

Long-term complications that can result from living with type 2 diabetes for many years include damage to the heart, blood vessels, and kidneys, and nerve damage that can affect eyesight and cause diabetic neuropathy.

In the study, called Look AHEAD, those who achieved diabetes remission had a 40 percent lower risk of cardiovascular disease and a 33 percent lower risk of kidney disease at the end of 12 years, according to the new report, published in Diabetologia.

This is most likely due to the results of weight loss, improvements in fitness, and lowering of A1C and low-density lipoprotein (LDL, or “bad”) cholesterol in the lifestyle intervention arm of the trial, says Gregg.

And the longer that people were able to maintain remission, the greater the benefit in terms of diabetes-related risk reduction, he stressed. Those who had evidence of at least four years of remission had 55 percent and 49 percent reductions in kidney and cardiovascular disease, respectively.

“This is the first study where we’ve shown the extended effects of remission on long-term diabetes complications. Our findings are very encouraging.”

Remission Isn’t Easy, but Even Temporary Reprieve Brings Benefits

The Look AHEAD study involved approximately 5,000 people with type 2 diabetes, around half of whom were assigned to an intensive lifestyle intervention segment. This consisted of weekly group and individual sessions in the first six months, to help participants reduce fat intake and total calorie intake by up to 1,800 calories per day, and to increase physical activity to around 175 minutes per week. The frequency of the sessions was reduced as the trial continued. By the end of the trial, participants attended training sessions only every two years.

The remaining half of the participants were given “diabetes education and support,” which consisted of three group sessions a year focusing on diet and physical activity goals.

Only 11 percent of the type 2 diabetes patients in the Look AHEAD study who were assigned to the intervention arm achieved remission one year into the study. Even fewer, 4 percent, were still in remission at 12 years, the study’s end. Participants with a short duration of type 2 diabetes, a low starting A1C, and a large magnitude of weight loss were most likely to experience remission.

Gregg stresses that remission isn’t easy; nor is it necessarily permanent.

“The majority of patients with type 2 diabetes are not going to achieve remission, but they can still gain these same health benefits through other means, such as managing risk factors well — blood pressure, glycemia (high blood sugar) and cholesterol, stopping smoking and things like that.”

“A healthy lifestyle is good at any point with type 2 diabetes. It’s going to have a benefit whether you achieve remission or not.”

As an illustration, Gregg notes that a few of the patients in the less intensive “diabetes, education and support arm” of Look AHEAD also achieved remission.

                             It's worth celebrating even temporarily getting your diabetes into remission.      iStock

It Doesn’t Matter How Remission Is Achieved

Look AHEAD was started 15 years ago, when doctors first realized that bariatric surgery (detailed at Diabetes Daily) was able to put type 2 diabetes into remission, and they wanted to see if this was possible through lifestyle intervention alone.

In the years since, research has explored alternative methods of achieving diabetes remission. Other contemporary methods include very low-carbohydrate diets (detailed at Diabetes Daily), meal replacement, such as the protocol for the ongoing DiRECT trial, or intermittent fasting.

It doesn’t really matter how remission is achieved, Gregg says, stressing that the goal is to remove use of all type 2 diabetes medications.

“[Look AHEAD is] the first intervention study to associate remission with reduction of diabetes-related complications, and this is encouraging news for those who can achieve remission from type 2 diabetes.”

And remission is still important even when only temporary, he says: “Our findings suggest any success with remission is associated with later health benefits.”

Can Ozempic and Mounjaro Create Diabetes Remission?

Asked whether the newer GLP-1 agonist drugs such as semaglutide (Ozempic) or tirzepatide (Mounjaro) should be counted when considering remission, Gregg is circumspect.

GLP-1 agonists appear to offer similar benefits to lifestyle interventions like those studied in the Look AHEAD trial. These drugs, which were first approved for type 2 diabetes for blood sugar reduction, can lead to a loss of up to 15 to 20 percent of body weight — approaching that achieved through bariatric surgery — and have also been shown to protect the heart and kidneys, per Diabetes Daily.

Technically, taking a GLP-1 agonist wouldn’t qualify for so-called type 2 diabetes remission because the goal of that is to remove all blood sugar–lowering medications, he explained.

And although people can now take GLP-1 agonists for obesity only, even if they don’t have diabetes, he quips, “I guess it’s a judgment call. Whether you call a GLP-1 agonist a diabetes medication or not.” But had GLP-1 agonists been available when Look AHEAD was conducted and a patient was taking one, “we would not have called that remission,” he concludes.

https://www.everydayhealth.com/type-2-diabetes/even-temporary-type-2-diabetes-remission-brings-huge-long-term-benefits/

Monday 22 January 2024

Diabetes Management Tips: 7 Bedtime Rituals To Control Blood Sugar Spike At Night

From thehealthsite.com

Suffering from diabetes? Here are 7 easy tips and tricks to curb night-time blood sugar spike effectively

Diabetes is a persistent issue for countless individuals around the world. Notorious for leading to elevated sugar levels in the blood, inappropriate management of this health condition may potentially result in several complications. Significant emphasis is placed on managing and reducing night-time blood sugar surges in comprehensive diabetes care. Here, we'll explore seven techniques to perform nightly, which may aid those struggling with diabetes in mastering their sugar levels, altogether contributing to their overall well-being.

                                                                         7 Bedtime Rituals To Control Blood Sugar Spike At Night

How To Control Blood Sugar Spike At Night?

Blood sugar spikes are common in the night time, which is why you must keep an eye out for managing your glucose levels with proper evening rituals.

Follow A Good Sleep Routine

Consistency in sleep cycles is key for individuals suffering from diabetes, as a regular sleep schedule keeps the body's internal timekeeper balanced and supports better control over blood sugar levels. Target 7-8 hours of restful sleep per night.

Reduce Your Carbohydrate Consumption At Night

Since carbohydrates can shoot up blood sugar levels quickly, reducing their intake before sleep can prevent unexpected increases in blood glucose. Opt for low-glycemic goodies or protein-packed snacks instead of carbohydrates.

Follow a Good Exercise Routine

Exercise is the diabetic's best friend - it helps enhance insulin sensitivity and maintains a grip on one's blood sugar levels. Include at least 30 minutes of moderate-intensity activities, such as speed walking, biking, or swimming into your daily routine to keep your sugar levels in check.

Keep Track of Your Blood Sugar Levels

Monitoring sugar levels is a staple for individuals with diabetes. Check your sugar levels before hitting the hay and modify your medicine or insulin dosage as needed. Writing down your daily blood glucose levels can help identify trends and tailor your diabetes management strategy.

Create A Calming Bed Routine

Given that stress may significantly increase blood sugar, it becomes crucial to shape a serene nightly routine to encourage a stress-free sleep experience, augmenting blood sugar management. You might want to try reading, soft music, deep breathing, or meditation before bed.

Avoid Caffeine Before Bed

Sleep-disrupting stimulants like caffeine and nicotine may promote unwanted surges in blood sugar. It is hence suggested to avoid these before sleep, and maybe opt for a cup of herbal tea or decaf drinks.

Nurture a Sleep-Friendly Space

Creating a conducive sleep environment greatly contributes to the quality of sleep and blood sugar management. Keep your room cool, dim, and distraction-free like electronic gadgets or bright lights. The use of blackout curtains or eye masks is encouraged to keep out external light.

Wrapping up, and effectively controlling blood sugar levels is fundamental for people with diabetes. By incorporating these seven evening habits, you can mitigate night-time sugar spikes and improve overall diabetes management. Remember to communicate with your healthcare professional for guidance on your personalized diabetes management.

https://www.thehealthsite.com/diseases-conditions/diabetes-management-tips-7-bedtime-rituals-to-control-blood-sugar-spike-at-night-1056468/