From verywellhealth.com
A lot of people connect blood sugar with metabolic health and diabetes, but there’s less discussion about blood sugar and your brain. So we spoke to our chief medical officer, Sohaib Imtiaz, MD, about how poor blood sugar regulation affects the brain and what we can do now to protect it in the long term.
*This interview has been edited and condensed for clarity.
Q: Why is managing your blood sugar so important for brain health?
Imtiaz: Your brain is actually the most metabolically demanding organ in the body. Even though it accounts for about 2% of your body weight, it consumes about 20% of your basal metabolic energy, and its primary fuel is glucose (sugar).
When you have diabetes or insulin resistance (a condition wherein your cells stop responding efficiently to the hormone that regulates blood sugar), it has a significant impact on your brain.
Some researchers have actually started calling Alzheimer’s disease “type 3 diabetes.” It’s an informal term, not an official diagnosis, but it captures just how important insulin signalling is in the brain.
Q: Is it just high blood sugar that is the problem?
Imtiaz: The constant swinging between high and low blood sugar readings, known as “glycaemic variability,” may be the biggest problem for brain health.
Ideally, your blood sugar should be between 70 and 180 mg/dL. Hyperglycaemia (high blood sugar) and hypoglycaemia (low blood sugar) occur when your glucose levels fall outside of the normal range.
Both high and low blood sugar contribute to cognitive dysfunction through different mechanisms.
Chronic hyperglycaemia causes inflammation in the brain and leads to a progressive decline in your brain cell connections, resulting in cognitive impairment. It also contributes to the loss of white matter in the brain, which can eventually lead to vascular dementia.
Since the brain relies so heavily on glucose, hypoglycaemia can disrupt brain functioning. Repeated episodes lead to structural brain changes affecting the brain’s prefrontal cortex, the region responsible for decision-making, and your hippocampus, the brain’s memory centre.
This is why it’s so important to work toward maintaining steady blood sugar levels rather than just aiming to keep it low.
Q: What are the top three simple habits you’d recommend to keep your blood sugar in check for better brain health?
Imtiaz: First, make balanced meals. Be sure to include protein, vegetables (fibre), and some healthy fat, such as olive oil, alongside carb-heavy foods. Fibre and fat are key to lowering glucose spikes from carbs.
Second, don’t sit down after you eat. Try to get up and walk around for a few minutes. It will help stabilize your blood sugar.
Third, get good sleep. When you’re sleep-deprived, you have a lot more blood sugar spikes the following day—even if you eat foods that don’t typically affect your blood sugar.
https://www.verywellhealth.com/how-blood-sugar-affects-brain-health-12007894
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