Tuesday, 1 July 2025

Managing body weight is key driver out of all lifestyle factors in reducing type 2 diabetes risk

From diabetes.co.uk/news

New research has demonstrated that while a number of healthy lifestyle behaviours can cut the risk of type 2 diabetes, managing body weight remains a key driver, particularly when it comes to different ethnic groups.

The risk of developing type 2 diabetes can be influenced by both a person’s genetics and their lifestyle, which includes dietalcohol intakesmoking and physical activity.

These behaviours can be combined into a lifestyle index to better predict diabetes risk.

However, previous studies only covered short follow-up periods so in this latest research, the team examined how combined lifestyle behaviours influence type 2 diabetes risk across different population groups over time, using a composite Lifestyle Risk Factor Index (LSRI).

A key finding was that participants in the study classed as obese – with a body mass index over 30 – were more than three times more likely to develop type 2 diabetes compared to those with a normal weight.


The international team of authors concluded that body mass index (BMI) had a stronger link with type 2 diabetes risk than LSRI, saying: “The LSRI’s significant association with type 2 diabetes risk persisted even after adjusting for BMI, indicating its independent significance.

“However, the influence of overweight and obesity on type 2 diabetes, when adjusted for LSRI, was notably stronger. This underscores that while LSRI captures key lifestyle factors affecting type 2 diabetes risk, BMI remains the strongest predictor.

“In summary, our study demonstrates significant ethnic differences in how lifestyle factors and BMI affect type 2 diabetes incidence.”

The research highlights how important it is to combine lifestyle habits through an index to assess diabetes risk.

The study group, which was made up of 165,383 participants, included European American, African American, Native Hawaiian, Japanese American, and Latino volunteers.

The research revealed that a higher LSRI score was associated with much lower type 2 diabetes incidence, particularly among the African American, Latino, and European American groups.

This suggests the need for public health programmes that are tailored to different ethnic groups.

https://www.diabetes.co.uk/news/2025/jun/managing-body-weight-is-key-driver-out-of-all-lifestyle-factors-in-reducing-type-2-diabetes-risk.html